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Regorafenib-nublexa

BAYER ZYDUS PHARMA PVT. LTD.

Regorafenib-nublexa


“Regorafenib" is the Drug / Molecule content in "Nublexa". Regorafenib is an oral multi-kinase inhibitor developed by Bayer which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. Regorafenib shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.

 


Indication

Regorafenib is indicated for the treatment of patients with metastatic colorectal cancer (CRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if RAS wild- type, an anti-EGFR therapy. It is also use to treat metastaticgastrointestinal stromal tumor (GIST) who have been previously treated with imatinib mesylate and sunitinib malate.

Note

Precaution

  • Nublexa is a prescription drug and should be used under proper medical guidance and advice.
  • Control hypertension before initiating treatment; monitor blood pressure regularly during treatment.
  • Advise females & males of reproductive potential to use effective contraception during treatment and for 2 months after final dose.
  • Increases risk for hemorrhage; discontinue therapy for severe or life-threatening hemorrhage.

Updated On Oct 21, 2019 by Admin

Strength

40 mg

Packing

1 X 28 Tablets (Bottle)

Storage

Store at room Temperature 25°C not Exceeding 30 °C



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