ROCHE
Esbriet-pirfenex
"Esbriet" contains the Drug / Molecule called “Pirfenidone”. Esbriet exhibits both anti-inflammatory and antifibrotic effects. Esbriet reduces fibroblast proliferation inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β. Esbriet also been shown to reduce production of inflammatory mediators such as TNF-α and IL-1β in both cultured cells and isolated human peripheral blood mononuclear cells.
“Pirfenex” is generic version of “Esbrite” and both contain same Drug / Molecule “Pirfenidone”.
Indication
Esbriet is used to treat mild to moderate forms of a certain lung disease called Idiopathic pulmonary fifrosis (IPF).
Note
Precaution
- Esbriet is a prescription drug and should be used under proper medical guidance and advice.
Strength
267 mg
Packing
270 Capsules (Bottle)
Storage
Store at room Temperature (25 C).
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Esbriet-pirfenex also available as
CIPLA LTD. (INDIA)
Pirfenex
"Pirfenex" contains the Drug / Molecule “Pirfenidone”. Pirfenex exhibits both anti-inflammatory and antifibrotic effects. Pirfenidone reduces fibroblast proliferation inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.Pirfenidone has also been shown to reduce production of inflammatory mediators such as TNF-α and IL-1β in both cultured cells and isolated human peripheral blood.