BAYER ZYDUS PHARMA PVT. LTD.
Regorafenib-nublexa
“Regorafenib" is the Drug / Molecule content in "Nublexa". Regorafenib is an oral multi-kinase inhibitor developed by Bayer which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. Regorafenib shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.
Indication
Regorafenib is indicated for the treatment of patients with metastatic colorectal cancer (CRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if RAS wild- type, an anti-EGFR therapy. It is also use to treat metastaticgastrointestinal stromal tumor (GIST) who have been previously treated with imatinib mesylate and sunitinib malate.
Note
Precaution
- Nublexa is a prescription drug and should be used under proper medical guidance and advice.
- Control hypertension before initiating treatment; monitor blood pressure regularly during treatment.
- Advise females & males of reproductive potential to use effective contraception during treatment and for 2 months after final dose.
- Increases risk for hemorrhage; discontinue therapy for severe or life-threatening hemorrhage.
Strength
40 mg
Packing
1 X 28 Tablets (Bottle)
Storage
Store at room Temperature 25°C not Exceeding 30 °C